The series title is borrowed from the unrelated 1909 Silas Weir Mitchell novel The Red City, and is in that context a reference to the red brick used for many of Philadelphia's buildings in the eighteenth century. Within the context of the series, the title refers to the blood of Philadelphia's many murder victims.
The series aired 108 episodes episodes over nine seasons, from 2012 to 2021.
- Aaron Douglas as Kevin Byrne
- Amber Chandler as Jessica Balzano
- Terry O'Quinn as Dwight Buchanan
- Kevin Rahm as Vincent Balzano
- Lucas Neff as Nick Palladino
- Ramón Rodríguez as Eric Chavez
- Kenneth Choi as Anthony Park
- Terrence Howard as John Shepherd
- Wentworth Miller as Patrick Farrell
- David Oyelowo as Simon Close